Compound class:
Synthetic organic
Comment: RP60556A is the most potent compound from the benzo[b]naphthyridones, a series of antibacterial compounds active against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) [1]. It was being developed as a topical treatment by Sanofi-Aventis but has been discontinued.
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References |
1. Tabart M, Picaut G, Desconclois JF, Dutka-Malen S, Huet Y, Berthaud N. (2001)
Synthesis and biological evaluation of benzo[b]naphthyridones, a series of new topical antibacterial agents. Bioorg Med Chem Lett, 11 (7): 919-21. [PMID:11294391] |