Synonyms: 4-methylpyrazole | Antizol®
fomepizole is an approved drug (FDA (1997))
Compound class:
Synthetic organic
Comment: Fomepizole is an alcohol dehydrogenase inhibitor.
|
|
References |
1. Fries RW, Bohlken DP, Plapp BV. (1979)
3-Substituted pyrazole derivatives as inhibitors and inactivators of liver alcohol dehydrogenase. J Med Chem, 22 (4): 356-9. [PMID:219196] |
2. Hansch C, Klein T, McClarin J, Langridge R, Cornell NW. (1986)
A quantitative structure-activity relationship and molecular graphics analysis of hydrophobic effects in the interactions of inhibitors with alcohol dehydrogenase. J Med Chem, 29 (5): 615-20. [PMID:2939242] |