Synonyms: compound B [WO2022002018A1] | LY-3499446
Compound class:
Synthetic organic
Comment: LY3499446 is a direct inhibitor of oncogenic KRAS mutant G12C that was developed for anticancer potential [1].
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References |
1. Uprety D, Adjei AA. (2020)
KRAS: From undruggable to a druggable Cancer Target. Cancer Treat Rev, 89: 102070. [PMID:32711246] |
2. Yu S, Li B. (2022)
Compound for inhibiting krasg12c mutant protein, preparation method therefor, and use thereof. Patent number: WO2022002018A1. Assignee: Suzhou Wentian Pharmaceutical Technology Co. Priority date: 03/07/2020. Publication date: 06/01/2022. |