Ligand id: 1234

Name: ranitidine

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Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 10
Topological polar surface area 108.88
Molecular weight 314.14
XLogP 1.28
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Beukers MW, Klaassen CH, De Grip WJ, Verzijl D, Timmerman H, Leurs R. (1997)
Heterologous expression of rat epitope-tagged histamine H2 receptors in insect Sf9 cells.
Br. J. Pharmacol., 122 (5): 867-74. [PMID:9384502]
2. Leurs R, Smit MJ, Menge WM, Timmerman H. (1994)
Pharmacological characterization of the human histamine H2 receptor stably expressed in Chinese hamster ovary cells.
Br. J. Pharmacol., 112 (3): 847-54. [PMID:7921611]