Synonyms: AZ-14066724 | AZ14066724 | AZD-9833 | AZD9833 | compound 28 PMID: 32910656]
Compound class:
Synthetic organic
Comment: Camizestrant (AZD9833) is an orally available selective estrogen receptor degrader (SERD) [1] that was developed for antineoplastic potential in ER+ve breast cancers.
![]() Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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References |
1. Scott JS, Moss TA, Balazs A, Barlaam B, Breed J, Carbajo RJ, Chiarparin E, Davey PRJ, Delpuech O, Fawell S et al.. (2020)
Discovery of AZD9833, a Potent and Orally Bioavailable Selective Estrogen Receptor Degrader and Antagonist. J Med Chem, 63 (23): 14530-14559. [PMID:32910656] |