Synonyms: amdinocillin | Coactin® | FL 1060 | Selexidin®
mecillinam is an approved drug (FDA (1984), UK (1979))
Compound class:
Synthetic organic
Comment: Mecillinam (USAN:amdinocillin) is s a semisynthetic, β-lactam antibacterial of the amidinopenicillin class [3].
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References |
1. Clarke PD, Geddes AM, McGhie D, Wall JC. (1976)
Mecillinam: a new antibiotic for enteric fever. Br Med J, 2 (6026): 14-5. [PMID:820402] |
2. Jansåker F, Frimodt-Møller N, Benfield TL, Knudsen JD. (2018)
Mecillinam for the treatment of acute pyelonephritis and bacteremia caused by Enterobacteriaceae: a literature review. Infect Drug Resist, 11: 761-771. [PMID:29872326] |
3. Lund F, Tybring L. (1972)
6 -amidinopenicillanic acids--a new group of antibiotics. Nat New Biol, 236 (66): 135-7. [PMID:4402006] |
4. Tybring L, Melchior NH. (1975)
Mecillinam (FL 1060), a 6beta-amidinopenicillanic acid derivative: bactericidal action and synergy in vitro. Antimicrob Agents Chemother, 8 (3): 271-6. [PMID:170856] |