Compound class:
Synthetic organic
Comment: AM1476 is a novel peripherally-acting serotonin 5‑HT2B receptor antagonist that was developed to reduce fibrosis-induced tissue damage and scarring. Example 49 in WO2016207231A1 represents the AM1476 racemate, and the hydrobromide formulation is example 50 [1].
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References |
1. Pettersson L. (2016)
Novel 5-ht2 antagonists. Patent number: WO2016207231A1. Assignee: Anamar Ab. Priority date: 22/06/2016. Publication date: 29/12/2016. |