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Synonyms: ADX 47273 | ADX47273
Compound class: Synthetic organic
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Gilmour G, Broad LM, Wafford KA, Britton T, Colvin EM, Fivush A, Gastambide F, Getman B, Heinz BA, McCarthy AP et al.. (2013)
In vitro characterisation of the novel positive allosteric modulators of the mGlu₅ receptor, LSN2463359 and LSN2814617, and their effects on sleep architecture and operant responding in the rat.
Neuropharmacology, 64: 224-39. [PMID:22884720]
2. Le Poul E, Bessis AS, Lutgens R, Bonnet B, Rocher JP, Epping-Jordan M, Mutel V. (2005)
In vitro pharmacological characterisation of selective mGluR5 positive allosteric modulators.
Neuropharmacology, 49 (S1): 252-.