Ligand id: 1528

Name: BIBO3304

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 10
Hydrogen bond donors 6
Rotatable bonds 16
Topological polar surface area 177.72
Molecular weight 529.28
XLogP 2.07
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

1. Dumont Y, Quirion R. (2000)
[(125)I]-GR231118: a high affinity radioligand to investigate neuropeptide Y Y(1) and Y(4) receptors.
Br J Pharmacol, 129: 37-46. [PMID:10694200]
2. Wieland HA, Engel W, Eberlein W, Rudolf K, Doods HN. (1998)
Subtype selectivity of the novel nonpeptide neuropeptide Y Y1 receptor antagonist BIBO 3304 and its effect on feeding in rodents.
Br. J. Pharmacol., 125: 549-555. [PMID:9806339]