7α-OAc-ginkgolide B

Ligand id: 1846

Name: 7α-OAc-ginkgolide B

Abbreviated name: 7α-OAc-GB

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 12
Hydrogen bond donors 3
Rotatable bonds 3
Topological polar surface area 175.12
Molecular weight 482.14
XLogP -0.35
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Vogensen SB, Stromgaard K, Shindou H, Jaracz S, Suehiro M, Ishii S, Shimizu T, Nakanishi K. (2003)
Preparation of 7-substituted ginkgolide derivatives: potent platelet activating factor (PAF) receptor antagonists.
J Med Chem, 46: 601-608. [PMID:12570381]