7α-OAc-ginkgolide B

Ligand id: 1846

Name: 7α-OAc-ginkgolide B

Abbreviated name: 7α-OAc-GB

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 12
Hydrogen bond donors 3
Rotatable bonds 3
Topological polar surface area 175.12
Molecular weight 482.14
XLogP -0.35
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

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Similar Ligands
tiotropium
Targets
M1 receptor; M2 receptor; M3 receptor
tetronothiodin
Targets
CCK2 receptor
alemcinal
Targets
motilin receptor
EM-523
Targets
motilin receptor
KOS1326
Targets
motilin receptor
ME36
Targets
motilin receptor
ME4
Targets
motilin receptor
ME67
Targets
motilin receptor
erythromycin
Targets
OATP1B3; motilin receptor
roxithromycin
Targets
motilin receptor
salvinorin A
Targets
κ receptor
10-OBn-7α-F-gingkolide B
Targets
PAF receptor
10-OBn-ginkgolide B
Targets
PAF receptor
10-OBn-ginkgolide C
Targets
PAF receptor
10-OBn-epi-ginkgolide C
Targets
PAF receptor
7α-Cl-ginkgolide B
Targets
PAF receptor
7α-F-ginkgolide B
Targets
PAF receptor
7α-N3-ginkgolide B
Targets
PAF receptor
7α-NH2-ginkgolide B
Targets
PAF receptor
7α-NHEt-ginkgolide B
Targets
PAF receptor
7α-NHMe-ginkgolide B
Targets
PAF receptor
7α-OCOCH2Ph-ginkgolide B
Targets
PAF receptor
7-epi-ginkgolide C
Targets
PAF receptor
ginkgolide A
Targets
Glycine Receptor (All subtypes); PAF receptor
ginkgolide B
Targets
5-HT3A; 5-HT3AB; Glycine Receptor (All subtypes); PAF receptor; glycine receptor α1 subunit; glycine receptor α2 subunit; glycine receptor α3 subunit; glycine receptor β subunit
ginkgolide C
Targets
Glycine Receptor (All subtypes); PAF receptor
ginkgolide J
Targets
Glycine Receptor (All subtypes); PAF receptor
picrotoxinin
Targets
5-HT3A; 5-HT3AB; Glycine Receptor (All subtypes); glycine receptor α1 subunit; glycine receptor α2 subunit; glycine receptor α3 subunit; glycine receptor β subunit
phorbol 12-myristate 13-acetate
Targets
KNa1.1; KNa1.2; Kir3.4; TRPV4
bilobalide
Targets
5-HT3A; 5-HT3AB; Glycine Receptor (All subtypes); glycine receptor α1 subunit; glycine receptor α2 subunit; glycine receptor β subunit
ivermectin
Targets
Glycine Receptor (All subtypes); P2X4; P2X7; nicotinic acetylcholine receptor α7 subunit
4α-PDD
Targets
TRPV4
bisandrographolide
Targets
TRPV4
correolide
Targets
Kv1.3
batrachotoxin
Targets
Nav1.1; Nav1.2; Nav1.3; Nav1.4; Nav1.5; Nav1.6; Nav1.7; Nav1.8
paclitaxel
Targets
Pregnane X receptor; TLR4; tubulin beta class I
triamcinolone acetonide
Targets
Glucocorticoid receptor
eplerenone
Targets
Mineralocorticoid receptor
zaragozic acid A
Targets
squalene synthase
zaragozic acid C
Targets
squalene synthase
compound 5d [PMID: 7966163]
Targets
squalene synthase
compound 6c [PMID: 7966163]
Targets
squalene synthase
compound 6d [PMID: 7966163]
Targets
squalene synthase
compound 4e [PMID: 7966163]
Targets
squalene synthase
compound 5d [PMID: 7966163]
Targets
squalene synthase
compound 16a [Sharratt et al., 1994]
Targets
squalene synthase
compound 3f [PMID: 7966163]
Targets
squalene synthase
L-735021
Targets
squalene synthase
compound 6g [PMID: 7966163]
Targets
squalene synthase
FR-49175
mitemcinal
Targets
motilin receptor
picrotoxin
Targets
5-HT3A; 5-HT3AB; GABAA receptor α3 subunit; GABAA receptor α5 subunit; GABAA receptor α6 subunit; GABAA receptor β1 subunit; GABAA receptor β3 subunit; GABAA receptor δ subunit; GABAA receptor γ2 subunit; GABAA receptor ρ1 subunit; GABAA receptor ρ2 subunit; GABAA receptor ρ3 subunit; glycine receptor α1 subunit; glycine receptor α2 subunit; glycine receptor β subunit... click on ligand to see complete list
1,9-dideoxyforskolin
Targets
VRAC
4α-PDH
Targets
TRPV4
ginkgolide X
Targets
glycine receptor α1 subunit; glycine receptor α2 subunit; glycine receptor β subunit
lubiprostone
Targets
ClC-2
picrotin
Targets
glycine receptor α1 subunit; glycine receptor α2 subunit; glycine receptor α3 subunit; glycine receptor β subunit
carboxyatractyloside
Targets
Mitochondrial adenine nucleotide translocator 1
glycyrrhizin
Targets
OATP1B1; OATP1B3
forskolin
cytochalasin B
okadaic acid
thapsigargin
everolimus
Targets
mechanistic target of rapamycin kinase
temsirolimus
Targets
mechanistic target of rapamycin kinase
beclometasone dipropionate
Targets
ADGRG3
sirolimus
Targets
FKBP prolyl isomerase 1A
wortmannin
Targets
mechanistic target of rapamycin kinase; phosphatidylinositol 4-kinase alpha; phosphatidylinositol 4-kinase beta; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; protein kinase, DNA-activated, catalytic subunit
zaragozic acid B
Targets
squalene synthase
bantag-1
Targets
BB1 receptor; BB2 receptor; BB3 receptor
azithromycin
pimecrolimus
Targets
FKBP prolyl isomerase 1A
tacrolimus
Targets
FKBP prolyl isomerase 1A
cabazitaxel
Targets
tubulin beta class I
docetaxel
Targets
tubulin beta class I
eribulin
Targets
tubulin beta class I
amcinonide
clobetasol propionate
Targets
Glucocorticoid receptor
desonide
diflorasone diacetate
Targets
Glucocorticoid receptor
flumethasone pivalate
flunisolide
Targets
Glucocorticoid receptor
fluocinolone acetonide
Targets
Glucocorticoid receptor
fluocinonide
Targets
Glucocorticoid receptor
fluticasone propionate
Targets
Glucocorticoid receptor; Mineralocorticoid receptor; Progesterone receptor
loteprednol etabonate
mitomycin C
budesonide
Targets
Glucocorticoid receptor; Mineralocorticoid receptor; Progesterone receptor
ingenol mebutate
Targets
protein kinase C alpha; protein kinase C beta; protein kinase C delta; protein kinase C epsilon; protein kinase C gamma
aclidinium
Targets
M1 receptor; M2 receptor; M3 receptor
ciclesonide
Targets
Glucocorticoid receptor
difluprednate
Targets
Glucocorticoid receptor
prednicarbate
fludroxycortide
ridaforolimus
Targets
mechanistic target of rapamycin kinase
sonolisib
zotarolimus
Targets
FKBP prolyl isomerase 1A
[3H]tiotropium
Targets
M2 receptor; M3 receptor
tirotundin
Targets
Peroxisome proliferator-activated receptor-γ
tagitinin A
Targets
Peroxisome proliferator-activated receptor-γ
compound 45 [PMID: 8709105]
Targets
adenylyl cyclase 1
TGN4
Targets
SERCA1
deflazacort
DMAMCL
Targets
pyruvate kinase M1/2
artemisinin
Targets
null
troleandomycin
Targets
CYP3A4
FD1
Targets
adenylyl cyclase 2
FD6
Targets
adenylyl cyclase 5
tonantzitlolone
Targets
TRPC4; TRPC5
cyclopamine-KAAD
Targets
SMO