Ligand id: 2018

Name: pasireotide

Structure and Physico-chemical Properties

2D Structure
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1. Cescato R, Loesch KA, Waser B, M├Ącke HR, Rivier JE, Reubi JC, Schonbrunn A. (2010)
Agonist-biased signaling at the sst2A receptor: the multi-somatostatin analogs KE108 and SOM230 activate and antagonize distinct signaling pathways.
Mol. Endocrinol., 24 (1): 240-9. [PMID:19910453]
2. Kao YJ, Ghosh M, Schonbrunn A. (2011)
Ligand-dependent mechanisms of sst2A receptor trafficking: role of site-specific phosphorylation and receptor activation in the actions of biased somatostatin agonists.
Mol. Endocrinol., 25 (6): 1040-54. [PMID:21493671]
3. Schmid HA, Schoeffter P. (2004)
Functional activity of the multiligand analog SOM230 at human recombinant somatostatin receptor subtypes supports its usefulness in neuroendocrine tumors.
Neuroendocrinology, 80 Suppl 1: 47-50. [PMID:15477717]