BIM 23056   Click here for help

GtoPdb Ligand ID: 2036

Compound class: Peptide or derivative
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
References
1. Bruns C, Raulf F, Hoyer D, Schloos J, Lübbert H, Weckbecker G. (1996)
Binding properties of somatostatin receptor subtypes.
Metab Clin Exp, 45 (8 Suppl 1): 17-20. [PMID:8769372]
2. Feuerbach D, Fehlmann D, Nunn C, Siehler S, Langenegger D, Bouhelal R, Seuwen K, Hoyer D. (2000)
Cloning, expression and pharmacological characterisation of the mouse somatostatin sst(5) receptor.
Neuropharmacology, 39 (8): 1451-62. [PMID:10818261]
3. Meyerhof W. (1998)
The elucidation of somatostatin receptor functions: a current view.
Rev Physiol Biochem Pharmacol, 133: 55-108. [PMID:9600011]
4. Patel YC, Srikant CB. (1994)
Subtype selectivity of peptide analogs for all five cloned human somatostatin receptors (hsstr 1-5).
Endocrinology, 135 (6): 2814-7. [PMID:7988476]
5. Raynor K, Murphy WA, Coy DH, Taylor JE, Moreau JP, Yasuda K, Bell GI, Reisine T. (1993)
Cloned somatostatin receptors: identification of subtype-selective peptides and demonstration of high affinity binding of linear peptides.
Mol Pharmacol, 43 (6): 838-44. [PMID:8100350]
6. Siehler S, Seuwen K, Hoyer D. (1998)
[125I]Tyr10-cortistatin14 labels all five somatostatin receptors.
Naunyn Schmiedebergs Arch Pharmacol, 357 (5): 483-9. [PMID:9650799]
7. Siehler S, Seuwen K, Hoyer D. (1998)
[125I][Tyr3]octreotide labels human somatostatin sst2 and sst5 receptors.
Eur J Pharmacol, 348 (2-3): 311-20. [PMID:9652348]
8. Siehler S, Seuwen K, Hoyer D. (1999)
Characterisation of human recombinant somatostatin receptors. 1. Radioligand binding studies.
Naunyn Schmiedebergs Arch Pharmacol, 360 (5): 488-99. [PMID:10598788]
9. Viollet C, Bodenant C, Prunotto C, Roosterman D, Schaefer J, Meyerhof W, Epelbaum J, Vaudry H, Leroux P. (1997)
Differential expression of multiple somatostatin receptors in the rat cerebellum during development.
J Neurochem, 68 (6): 2263-72. [PMID:9166718]