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Synonyms: GR-159,897 | GR-159897 | GR159897
Compound class: Synthetic organic
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Beresford IJ, Sheldrick RL, Ball DI, Turpin MP, Walsh DM, Hawcock AB, Coleman RA, Hagan RM, Tyers MB. (1995)
GR159897, a potent non-peptide antagonist at tachykinin NK2 receptors.
Eur. J. Pharmacol., 272 (2-3): 241-8. [PMID:7713168]
2. Emonds-Alt X, Golliot F, Pointeau P, Le Fur G, Breliere JC. (1993)
Characterization of the binding sites of [3H]SR 48968, a potent nonpeptide radioligand antagonist of the neurokinin-2 receptor.
Biochem. Biophys. Res. Commun., 191 (3): 1172-7. [PMID:7682062]
3. Smith PW, Cooper AW, Bell R, Beresford IJ, Gore PM, McElroy AB, Pritchard JM, Saez V, Taylor NR, Sheldrick RL. (1995)
New spiropiperidines as potent and selective non-peptide tachykinin NK2 receptor antagonists.
J. Med. Chem., 38 (19): 3772-9. [PMID:7562907]