H-8   

GtoPdb Ligand ID: 2348

Compound class: Synthetic organic
2D Structure
Click here for structure editor
Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 79.47
Molecular weight 265.09
XLogP 0.5
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Canonical SMILES CNCCNS(=O)(=O)c1cccc2c1ccnc2
Isomeric SMILES CNCCNS(=O)(=O)c1cccc2c1ccnc2
InChI InChI=1S/C12H15N3O2S/c1-13-7-8-15-18(16,17)12-4-2-3-10-9-14-6-5-11(10)12/h2-6,9,13,15H,7-8H2,1H3
InChI Key PJWUXKNZVMEPPH-UHFFFAOYSA-N
References
1. Wei JY, Cohen ED, Barnstable CJ. (1997)
Direct blockade of both cloned rat rod photoreceptor cyclic nucleotide-gated non-selective cation (CNG) channel alpha-subunit and native CNG channels from Xenopus rod outer segments by H-8, a non-specific cyclic nucleotide-dependent protein kinase inhibitor.
Neurosci. Lett., 233 (1): 37-40. [PMID:9324234]