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Compound class: Natural product or derivative
Comment: From garlic
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Bautista DM, Movahed P, Hinman A, Axelsson HE, Sterner O, Högestätt ED, Julius D, Jordt SE, Zygmunt PM. (2005)
Pungent products from garlic activate the sensory ion channel TRPA1.
Proc Natl Acad Sci USA, 102 (34): 12248-52. [PMID:16103371]
2. Macpherson LJ, Geierstanger BH, Viswanath V, Bandell M, Eid SR, Hwang S, Patapoutian A. (2005)
The pungency of garlic: activation of TRPA1 and TRPV1 in response to allicin.
Curr Biol, 15 (10): 929-34. [PMID:15916949]