mosapride   Click here for help

GtoPdb Ligand ID: 242

Approved drug
mosapride is an approved drug
Compound class: Synthetic organic
Comment: Marketed formulations contain mosapride citrate (PubChem CID 119583).
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 76.82
Molecular weight 421.16
XLogP 2.93
No. Lipinski's rules broken 0
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Canonical SMILES CCOc1cc(N)c(cc1C(=O)NCC1OCCN(C1)Cc1ccc(cc1)F)Cl
Isomeric SMILES CCOc1cc(N)c(cc1C(=O)NCC1OCCN(C1)Cc1ccc(cc1)F)Cl
InChI InChI=1S/C21H25ClFN3O3/c1-2-28-20-10-19(24)18(22)9-17(20)21(27)25-11-16-13-26(7-8-29-16)12-14-3-5-15(23)6-4-14/h3-6,9-10,16H,2,7-8,11-13,24H2,1H3,(H,25,27)
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Structure of the human serotonin 5-HT4 receptor gene and cloning of a novel 5-HT4 splice variant.
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Mosapride in gastrointestinal disorders.
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Systematic review: cardiovascular safety profile of 5-HT(4) agonists developed for gastrointestinal disorders.
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