prucalopride   Click here for help

GtoPdb Ligand ID: 243

Synonyms: Motegrity® | R-093877 | R-108512 | Resolor®
Approved drug
prucalopride is an approved drug (EMA (2009), FDA (2018))
Compound class: Synthetic organic
Comment: Prucalopride is a serotonin 5-HT4 receptor agonist.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 76.82
Molecular weight 367.17
XLogP 1.56
No. Lipinski's rules broken 0
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Canonical SMILES COCCCN1CCC(CC1)NC(=O)c1cc(Cl)c(c2c1OCC2)N
Isomeric SMILES COCCCN1CCC(CC1)NC(=O)c1cc(Cl)c(c2c1OCC2)N
InChI InChI=1S/C18H26ClN3O3/c1-24-9-2-6-22-7-3-12(4-8-22)21-18(23)14-11-15(19)16(20)13-5-10-25-17(13)14/h11-12H,2-10,20H2,1H3,(H,21,23)
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