adenosine 5'-monophosphate

Ligand id: 2455

Name: adenosine 5'-monophosphate

Abbreviated name: AMP

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 11
Hydrogen bond donors 5
Rotatable bonds 4
Topological polar surface area 195.88
Molecular weight 347.06
XLogP -3.08
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Cool B, Zinker B, Chiou W, Kifle L, Cao N, Perham M, Dickinson R, Adler A, Gagne G, Iyengar R et al.. (2006)
Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome.
Cell Metab., 3 (6): 403-16. [PMID:16753576]
2. Nilius B, Prenen J, Voets T, Droogmans G. (2004)
Intracellular nucleotides and polyamines inhibit the Ca2+-activated cation channel TRPM4b.
Pflugers Arch., 448 (1): 70-5. [PMID:14758478]