Synonyms: LS-190926
Compound class:
Synthetic organic
![]() Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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References |
1. Schroeder BC, Hechenberger M, Weinreich F, Kubisch C, Jentsch TJ. (2000)
KCNQ5, a novel potassium channel broadly expressed in brain, mediates M-type currents. J Biol Chem, 275 (31): 24089-95. [PMID:10816588] |
2. Søgaard R, Ljungstrøm T, Pedersen KA, Olesen SP, Jensen BS. (2001)
KCNQ4 channels expressed in mammalian cells: functional characteristics and pharmacology. Am J Physiol, Cell Physiol, 280 (4): C859-66. [PMID:11245603] |
3. Wang HS, Brown BS, McKinnon D, Cohen IS. (2000)
Molecular basis for differential sensitivity of KCNQ and I(Ks) channels to the cognitive enhancer XE991. Mol Pharmacol, 57 (6): 1218-23. [PMID:10825393] |
4. Wang HS, Pan Z, Shi W, Brown BS, Wymore RS, Cohen IS, Dixon JE, McKinnon D. (1998)
KCNQ2 and KCNQ3 potassium channel subunits: molecular correlates of the M-channel. Science, 282 (5395): 1890-3. [PMID:9836639] |