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Synonyms: GC 1 compound | GC-1 | QRX-431
Compound class: Synthetic organic
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Chiellini G, Apriletti JW, Yoshihara HA, Baxter JD, Ribeiro RC, Scanlan TS. (1998)
A high-affinity subtype-selective agonist ligand for the thyroid hormone receptor.
Chem. Biol., 5 (6): 299-306. [PMID:9653548]
2. Schueler PA, Schwartz HL, Strait KA, Mariash CN, Oppenheimer JH. (1990)
Binding of 3,5,3'-triiodothyronine (T3) and its analogs to the in vitro translational products of c-erbA protooncogenes: differences in the affinity of the alpha- and beta-forms for the acetic acid analog and failure of the human testis and kidney alpha-2 products to bind T3.
Mol. Endocrinol., 4 (2): 227-34. [PMID:2158622]
3. Sharma SK, Klee WA, Nirenberg M. (1977)
Opiate-dependent modulation of adenylate cyclase.
Proc. Natl. Acad. Sci. U.S.A., 74 (8): 3365-9. [PMID:269396]