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Compound class: Synthetic organic
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Blair JB, Kurrasch-Orbaugh D, Marona-Lewicka D, Cumbay MG, Watts VJ, Barker EL, Nichols DE. (2000)
Effect of ring fluorination on the pharmacology of hallucinogenic tryptamines.
J. Med. Chem., 43 (24): 4701-10. [PMID:11101361]
2. Kalipatnapu S, Pucadyil TJ, Harikumar KG, Chattopadhyay A. (2004)
Ligand binding characteristics of the human serotonin1A receptor heterologously expressed in CHO cells.
Biosci. Rep., 24 (2): 101-15. [PMID:15628665]
3. Newman-Tancredi A, Cussac D, Audinot V, Millan MJ. (1999)
Actions of roxindole at recombinant human dopamine D2, D3 and D4 and serotonin 5-HT1A, 5-HT1B and 5-HT1D receptors.
Naunyn Schmiedebergs Arch. Pharmacol., 359 (6): 447-53. [PMID:10431754]
4. Newman-Tancredi A, Verrièle L, Chaput C, Millan MJ. (1998)
Labelling of recombinant human and native rat serotonin 5-HT1A receptors by a novel, selective radioligand, [3H]-S 15535: definition of its binding profile using agonists, antagonists and inverse agonists.
Naunyn Schmiedebergs Arch. Pharmacol., 357 (3): 205-17. [PMID:9550290]