Ligand id: 3364

Name: diazepam

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Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 1
Topological polar surface area 32.67
Molecular weight 284.07
XLogP 2.92
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

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Use of receptor antagonist in elucidating the mechanism of action of TRH in GH3 cells.
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Drug Interactions: Cytochrome P450 Drug Interaction Table. Indiana University School of Medicine (2007).
Accessed on 18/11/2014. Modified on 18/11/2014. http://medicine.iupui.edu/clinpharm/ddis/clinical-table/
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Interaction of H+ and Zn2+ on recombinant and native rat neuronal GABAA receptors.
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4. Pritchett DB, L├╝ddens H, Seeburg PH. (1989)
Type I and type II GABAA-benzodiazepine receptors produced in transfected cells.
Science, 245 (4924): 1389-92. [PMID:2551039]