- Advanced search
- Immuno Portal
- Malaria Portal
Synonyms: 2-phenylethynyl-NECA | 2-phenylethynylNECA
Compound class: Synthetic organic
Comment: There is some variation in the structure for this compound represented on other databases. The structure shown here is that represented in the references  and  and on ChEMBL.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Klotz KN, Camaioni E, Volpini R, Kachler S, Vittori S, Cristalli G. (1999)
2-Substituted N-ethylcarboxamidoadenosine derivatives as high-affinity agonists at human A3 adenosine receptors.
Naunyn Schmiedebergs Arch Pharmacol, 360 (2): 103-8. [PMID:10494877]
2. Volpini R, Costanzi S, Lambertucci C, Taffi S, Vittori S, Klotz KN, Cristalli G. (2002)
N(6)-alkyl-2-alkynyl derivatives of adenosine as potent and selective agonists at the human adenosine A(3) receptor and a starting point for searching A(2B) ligands.
J Med Chem, 45 (15): 3271-9. [PMID:12109910]