donitriptan

Ligand id: 39

Name: donitriptan

Structure and Physico-chemical Properties

2D Structure
Click here for structure editor
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 98.38
Molecular weight 403.2
XLogP 2.29
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. John GW, Pauwels PJ, Perez M, Halazy S, Le Grand B, Verscheure Y, Valentin JP, Palmier C, Wurch T, Chopin P et al.. (1999)
F 11356, a novel 5-hydroxytryptamine (5-HT) derivative with potent, selective, and unique high intrinsic activity at 5-HT1B/1D receptors in models relevant to migraine.
J. Pharmacol. Exp. Ther., 290 (1): 83-95. [PMID:10381763]