Ligand id: 4088

Name: [3H]MDL105519    

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 4
Topological polar surface area 90.39
Molecular weight 375.01
XLogP 4.71
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Chazot PL, Reiss C, Chopra B, Stephenson FA. (1998)
[3H]MDL 105,519 binds with equal high affinity to both assembled and unassembled NR1 subunits of the NMDA receptor.
Eur. J. Pharmacol., 353 (1): 137-40. [PMID:9721050]