iberiotoxin

Ligand id: 4218

Name: iberiotoxin

Structure and Physico-chemical Properties

2D Structure
References
1. Li W, Gao SB, Lv CX, Wu Y, Guo ZH, Ding JP, Xu T. (2007)
Characterization of voltage-and Ca2+-activated K+ channels in rat dorsal root ganglion neurons.
J. Cell. Physiol., 212 (2): 348-57. [PMID:17523149]
2. Lippiat JD, Standen NB, Harrow ID, Phillips SC, Davies NW. (2003)
Properties of BK(Ca) channels formed by bicistronic expression of hSloalpha and beta1-4 subunits in HEK293 cells.
J. Membr. Biol., 192 (2): 141-8. [PMID:12682801]
3. Löhn M, Lauterbach B, Haller H, Pongs O, Luft FC, Gollasch M. (2001)
beta(1)-Subunit of BK channels regulates arterial wall[Ca(2+)] and diameter in mouse cerebral arteries.
J. Appl. Physiol., 91 (3): 1350-4. [PMID:11509535]
4. Pethő Z, Tanner MR, Tajhya RB, Huq R, Laragione T, Panyi G, Gulko PS, Beeton C. (2016)
Different expression of β subunits of the KCa1.1 channel by invasive and non-invasive human fibroblast-like synoviocytes.
Arthritis Res. Ther., 18 (1): 103. [PMID:27165430]
5. Tanner MR, Pennington MW, Chamberlain BH, Huq R, Gehrmann EJ, Laragione T, Gulko PS, Beeton C. (2018)
Targeting KCa1.1 Channels with a Scorpion Venom Peptide for the Therapy of Rat Models of Rheumatoid Arthritis.
J. Pharmacol. Exp. Ther., 365 (2): 227-236. [PMID:29453198]
6. Wang B, Jaffe DB, Brenner R. (2014)
Current understanding of iberiotoxin-resistant BK channels in the nervous system.
Front Physiol, 5: 382. [PMID:25346692]