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Compound class: Synthetic organic
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Jacobson KA, Park KS, Jiang JL, Kim YC, Olah ME, Stiles GL, Ji XD. (1997)
Pharmacological characterization of novel A3 adenosine receptor-selective antagonists.
Neuropharmacology, 36 (9): 1157-65. [PMID:9364471]
2. Jiang JL, van Rhee AM, Melman N, Ji XD, Jacobson KA. (1996)
6-phenyl-1,4-dihydropyridine derivatives as potent and selective A3 adenosine receptor antagonists.
J Med Chem, 39 (23): 4667-75. [PMID:8917655]
3. Li AH, Moro S, Melman N, Ji XD, Jacobson KA. (1998)
Structure-activity relationships and molecular modeling of 3, 5-diacyl-2,4-dialkylpyridine derivatives as selective A3 adenosine receptor antagonists.
J Med Chem, 41 (17): 3186-201. [PMID:9703464]
4. Liang BT, Urso R, Sambraski E, Jacobson KA. (2010)
. In A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics
Edited by Borea PA (Springer) . [ISBN:9789048131440]