brain natriuretic peptide

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Ligands
brain natriuretic peptide (Human)

GtoPdb Ligand ID: 4890

Abbreviated name: BNP

Synonyms: BNP(1-32) | BNP-32 | brain natriuretic peptide 32 | Natrecor®

brain natriuretic peptide is an approved drug (FDA (2001))

Compound class: Endogenous peptide in human, mouse or rat

Comment: Nesiritide is the recombinant form of human brain natriuretic peptide.

Species: Human

View more information in the IUPHAR Pharmacology Education Project: brain natriuretic peptide

References
1. Olson LJ, Lowe DG, Drewett JG. (1996) Novel natriuretic peptide receptor/guanylyl cyclase A-selective agonist inhibits angiotensin II- and forskolin-evoked aldosterone synthesis in a human zona glomerulosa cell line. Mol Pharmacol, 50 (2): 430-5. [PMID:8700153]
2. Suga S, Nakao K, Hosoda K, Mukoyama M, Ogawa Y, Shirakami G, Arai H, Saito Y, Kambayashi Y, Inouye K. (1992) Receptor selectivity of natriuretic peptide family, atrial natriuretic peptide, brain natriuretic peptide, and C-type natriuretic peptide. Endocrinology, 130 (1): 229-39. [PMID:1309330]

References

1. Olson LJ, Lowe DG, Drewett JG. (1996)
Novel natriuretic peptide receptor/guanylyl cyclase A-selective agonist inhibits angiotensin II- and forskolin-evoked aldosterone synthesis in a human zona glomerulosa cell line.
Mol Pharmacol, 50 (2): 430-5. [PMID:8700153]

2. Suga S, Nakao K, Hosoda K, Mukoyama M, Ogawa Y, Shirakami G, Arai H, Saito Y, Kambayashi Y, Inouye K. (1992)
Receptor selectivity of natriuretic peptide family, atrial natriuretic peptide, brain natriuretic peptide, and C-type natriuretic peptide.
Endocrinology, 130 (1): 229-39. [PMID:1309330]