EHNA   

GtoPdb Ligand ID: 5179

Synonyms: erythro-9-(2-hydroxy-3-nonyl)adenine hydrochloride
Compound class: Synthetic organic
2D Structure
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SMILES / InChI / InChIKey
Canonical SMILES CCCCCCC(n1cnc2c1ncnc2[NH3+])C(O)C.[Cl-]
Isomeric SMILES CCCCCC[C@H](n1cnc2c1ncnc2[NH3+])[C@H](O)C.[Cl-]
InChI InChI=1S/C14H23N5O.ClH/c1-3-4-5-6-7-11(10(2)20)19-9-18-12-13(15)16-8-17-14(12)19;/h8-11,20H,3-7H2,1-2H3,(H2,15,16,17);1H/t10-,11+;/m1./s1
InChI Key VVDXNJRUNJMYOZ-DHXVBOOMSA-N
References
1. Agarwal RP, Spector T, Parks Jr RE. (1977)
Tight-binding inhibitors--IV. Inhibition of adenosine deaminases by various inhibitors.
Biochem. Pharmacol., 26 (5): 359-67. [PMID:849330]
2. Michie AM, Lobban M, Müller T, Harnett MM, Houslay MD. (1996)
Rapid regulation of PDE-2 and PDE-4 cyclic AMP phosphodiesterase activity following ligation of the T cell antigen receptor on thymocytes: analysis using the selective inhibitors erythro-9-(2-hydroxy-3-nonyl)-adenine (EHNA) and rolipram.
Cell. Signal., 8 (2): 97-110. [PMID:8730511]