BRL 44408

Ligand id: 525

Name: BRL 44408

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 27.63
Molecular weight 215.14
XLogP 1.42
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. UhlĂ©n S, Porter AC, Neubig RR. (1994)
The novel alpha-2 adrenergic radioligand [3H]-MK912 is alpha-2C selective among human alpha-2A, alpha-2B and alpha-2C adrenoceptors.
J. Pharmacol. Exp. Ther., 271 (3): 1558-65. [PMID:7996470]
2. Young P, Berge J, Chapman H, Cawthorne MA. (1989)
Novel alpha 2-adrenoceptor antagonists show selectivity for alpha 2A- and alpha 2B-adrenoceptor subtypes.
Eur. J. Pharmacol., 168 (3): 381-6. [PMID:2573535]