LK 204-545

Ligand id: 544

Name: LK 204-545

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 5
Rotatable bonds 17
Topological polar surface area 145.1
Molecular weight 484.23
XLogP 1.36
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Louis SN, Nero TL, Iakovidis D, Jackman GP, Louis WJ. (1999)
LK 204-545, a highly selective beta1-adrenoceptor antagonist at human beta-adrenoceptors.
Eur. J. Pharmacol., 367 (2-3): 431-5. [PMID:10079020]