MK 6892

Ligand id: 5788

Name: MK 6892

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 7
Topological polar surface area 138.44
Molecular weight 386.16
XLogP 1.52
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Shen HC, Ding FX, Raghavan S, Deng Q, Luell S, Forrest MJ, Carballo-Jane E, Wilsie LC, Krsmanovic ML, Taggart AK et al.. (2010)
Discovery of a biaryl cyclohexene carboxylic acid (MK-6892): a potent and selective high affinity niacin receptor full agonist with reduced flushing profiles in animals as a preclinical candidate.
J. Med. Chem., 53 (6): 2666-70. [PMID:20184326]