Ligand id: 6217

Name: ADX71743

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 43.1
Molecular weight 269.14
XLogP 2.9
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Kalinichev M, Rouillier M, Girard F, Royer-Urios I, Bournique B, Finn T, Charvin D, Campo B, Le Poul E, Mutel V et al.. (2013)
ADX71743, a potent and selective negative allosteric modulator of metabotropic glutamate receptor 7: in vitro and in vivo characterization.
J. Pharmacol. Exp. Ther., 344 (3): 624-36. [PMID:23257312]