Ligand id: 6219

Name: MNI-135

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 65.25
Molecular weight 401
XLogP 3.05
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Hemstapat K, Da Costa H, Nong Y, Brady AE, Luo Q, Niswender CM, Tamagnan GD, Conn PJ. (2007)
A novel family of potent negative allosteric modulators of group II metabotropic glutamate receptors.
J. Pharmacol. Exp. Ther., 322 (1): 254-64. [PMID:17416742]