drotrecogin alfa   Click here for help

GtoPdb Ligand ID: 6788

Synonyms: drotrecogin alfa (activated) | HSDB 7366 | Xigris®
Approved drug
drotrecogin alfa is an approved drug (FDA (2001), EMA (2009))
Comment: Drotrecogin alfa (activated) is a recombinant form of human activated protein C.
References
1. Kanji S, Devlin JW, Piekos KA, Racine E. (2001)
Recombinant human activated protein C, drotrecogin alfa (activated): a novel therapy for severe sepsis.
Pharmacotherapy, 21 (11): 1389-402. [PMID:11714212]
2. Kapur S, Kupfer Y, Tessler S. (2001)
Recombinant human activated protein C for severe sepsis.
N Engl J Med, 345 (3): 219-20; author reply 220-1. [PMID:11463021]