methylprednisolone

Ligand id: 7088

Name: methylprednisolone

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Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 2
Topological polar surface area 94.83
Molecular weight 374.21
XLogP 1.52
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Auerbach SS, DrugMatrix® and ToxFX® Coordinator National Toxicology Program. 
National Toxicology Program: Dept of Health and Human Services.
Accessed on 02/05/2014. Modified on 02/05/2014. DrugMatrix, https://ntp.niehs.nih.gov/drugmatrix/index.html
2. Beckmann H, Richter J, Hill K, Urban N, Lemoine H, Schaefer M. (2017)
A benzothiadiazine derivative and methylprednisolone are novel and selective activators of transient receptor potential canonical 5 (TRPC5) channels.
Cell Calcium, 66: 10-18. [PMID:28807145]