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Synonyms: Medrol® | U-67590A
methylprednisolone is an approved drug (FDA (1957))
Compound class: Metabolite or derivative
Comment: Methylprednisolone is a corticosteroid.
Marketed formulations may contain methylprednisolone acetate (PubChem CID 5877).
Methylprednisolone has been reported to activate the TRPC5 ion channel . Methylprednisolone-induced activation of TRPC5 is long lasting, reversible and sensitive to the TRPC5 inhibitor clemizole .
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
View more information in the IUPHAR Pharmacology Education Project: methylprednisolone
|Compound class||Metabolite or derivative|
|Approved drug?||Yes (FDA (1957))|
|WHO Essential Medicine||WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.|
|International Nonproprietary Names|
|Medrol® | U-67590A|
|CAS Registry No.||83-43-2|
|GtoPdb PubChem SID||178103666|
|Search Google for chemical match using the InChIKey||VHRSUDSXCMQTMA-PJHHCJLFSA-N|
|Search Google for chemicals with the same backbone||VHRSUDSXCMQTMA|
|Search PubMed clinical trials||methylprednisolone|
|Search PubMed titles||methylprednisolone|
|Search PubMed titles/abstracts||methylprednisolone|
|Search UniChem for chemical match using the InChIKey||VHRSUDSXCMQTMA-PJHHCJLFSA-N|
|Search UniChem for chemicals with the same backbone||VHRSUDSXCMQTMA|
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Cat. No. 4819