L-lysine

Ligand id: 724

Name: L-lysine

Abbreviated name: L-Lys

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 89.34
Molecular weight 146.11
XLogP -2.95
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Fiermonte G, Dolce V, David L, Santorelli FM, Dionisi-Vici C, Palmieri F, Walker JE. (2003)
The mitochondrial ornithine transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution of two human isoforms.
J. Biol. Chem., 278 (35): 32778-83. [PMID:12807890]
2. Hatanaka T, Huang W, Ling R, Prasad PD, Sugawara M, Leibach FH, Ganapathy V. (2001)
Evidence for the transport of neutral as well as cationic amino acids by ATA3, a novel and liver-specific subtype of amino acid transport system A.
Biochim. Biophys. Acta, 1510 (1-2): 10-7. [PMID:11342143]
3. Wellendorph P, Hansen KB, Balsgaard A, Greenwood JR, Egebjerg J, Brauner-Osborne H. (2005)
Deorphanization of GPRC6A: a promiscuous L-alpha-amino acid receptor with preference for basic amino acids.
Mol Pharmacol., 67: 589-597. [PMID:15576628]