Ligand id: 724

Name: L-lysine

Abbreviated name: L-Lys

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 89.34
Molecular weight 146.11
XLogP -2.95
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Natural/Endogenous Targets
GPRC6 receptor
Transporters Moving this Compound Across a Lipid Membrane
Transporter EC number Reaction Reference
Cationic amino acid transporter 3
Mitochondrial ornithine transporter 2 1
High affinity cationic amino acid transporter 1
Mitochondrial ornithine transporter 1 1
Low affinity cationic amino acid transporter 2
sodium-coupled neutral amino acid transporter 4 2
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
GPRC6 receptor Hs Agonist Full agonist 3.8 pEC50 - 3
pEC50 3.8 [3]
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
Ligand mentioned in the following text fields