Ligand id: 7252

Name: oxaprozin

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 63.33
Molecular weight 293.11
XLogP 3.67
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Kawai S, Nishida S, Kato M, Furumaya Y, Okamoto R, Koshino T, Mizushima Y. (1998)
Comparison of cyclooxygenase-1 and -2 inhibitory activities of various nonsteroidal anti-inflammatory drugs using human platelets and synovial cells.
Eur. J. Pharmacol., 347 (1): 87-94. [PMID:9650852]
2. Klingler FM, Wolf M, Wittmann S, Gribbon P, Proschak E. (2016)
Bacterial Expression and HTS Assessment of Soluble Epoxide Hydrolase Phosphatase.
J Biomol Screen, 21 (7): 689-94. [PMID:27009944]