- Advanced search
- Immuno Portal
- Malaria Portal
Synonyms: CP-16171 | Feldene®
piroxicam is an approved drug (FDA (1982))
Compound class: Synthetic organic
Comment: Piroxicam is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic activity.
Drug formulations contain β-cyclodextrin to increase bioavailability eg piroxicam betadex has PubChem CID 54723875.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
View more information in the IUPHAR Pharmacology Education Project: piroxicam
1. Lazer ES, Miao CK, Cywin CL, Sorcek R, Wong HC, Meng Z, Potocki I, Hoermann M, Snow RJ, Tschantz MA et al.. (1997)
Effect of structural modification of enol-carboxamide-type nonsteroidal antiinflammatory drugs on COX-2/COX-1 selectivity.
J Med Chem, 40 (6): 980-9. [PMID:9083488]
2. Wilkerson WW, Copeland RA, Covington M, Trzaskos JM. (1995)
Antiinflammatory 4,5-diarylpyrroles. 2. Activity as a function of cyclooxygenase-2 inhibition.
J Med Chem, 38 (20): 3895-901. [PMID:7562922]