Ligand id: 7310

Name: tolazoline

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 24.39
Molecular weight 160.1
XLogP 1.5
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Jasper JR, Lesnick JD, Chang LK, Yamanishi SS, Chang TK, Hsu SA, Daunt DA, Bonhaus DW, Eglen RM. (1998)
Ligand efficacy and potency at recombinant alpha2 adrenergic receptors: agonist-mediated [35S]GTPgammaS binding.
Biochem. Pharmacol., 55 (7): 1035-43. [PMID:9605427]
2. Teskin O, Uydeş-Dogan BS, Enç Y, Alp FI, Kaleli D, Keser S, Iyigün T, Bilgen F, Dagsali S, Ozdemir O. (2006)
Comparative effects of tolazoline and nitroprusside on human isolated radial artery.
Ann. Thorac. Surg., 81 (1): 125-31. [PMID:16368348]