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Synonyms: CDB-2914 | EllaOne® | VA2914
ulipristal acetate is an approved drug (EMA (2009), FDA (2010))
Compound class: Natural product or derivative
Comment: Ulipristal acetate is a selective progesterone receptor modulator (SPRM) contained in certain emergency contraceptives.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
View more information in the IUPHAR Pharmacology Education Project: ulipristal acetate
1. Attardi BJ, Burgenson J, Hild SA, Reel JR. (2004)
In vitro antiprogestational/antiglucocorticoid activity and progestin and glucocorticoid receptor binding of the putative metabolites and synthetic derivatives of CDB-2914, CDB-4124, and mifepristone.
J Steroid Biochem Mol Biol, 88 (3): 277-88. [PMID:15120421]
2. Rewinkel J, Enthoven M, Golstein I, van der Rijst M, Scholten A, van Tilborg M, de Weys D, Wisse J, Hamersma H. (2008)
11-(pyridinylphenyl)steroids--a new class of mixed-profile progesterone agonists/antagonists.
Bioorg Med Chem, 16 (6): 2753-63. [PMID:18243712]