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Synonyms: Acuphase® | cis(Z)-cloflupentixol | Cisordinol® | Clopixol® | NSC 64087 | NSC169185
zuclopenthixol is an approved drug
Compound class: Synthetic organic
Comment: Zuclopenthixol is a thioxanthene class typical antipsychotic. Chemically it is the cis-isomer of clopenthixol. The CAS registry number (53772-83-1) submitted with the WHO INN record for zuclopenthixol maps to PubChem CID 5311507.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
View more information in the IUPHAR Pharmacology Education Project: zuclopenthixol
1. Arnt J, Hyttel J. (1984)
Differential inhibition by dopamine D-1 and D-2 antagonists of circling behaviour induced by dopamine agonists in rats with unilateral 6-hydroxydopamine lesions.
Eur J Pharmacol, 102 (2): 349-54. [PMID:6148252]
2. Nyberg S, Farde L, Bartfai A, Halldin C. (1995)
Central D2 receptor occupancy and effects of zuclopenthixol acetate in humans.
Int Clin Psychopharmacol, 10 (4): 221-7. [PMID:8748043]