CCL19   Click here for help

GtoPdb Ligand ID: 810

Synonyms: β-chemokine exodus-3 | ck β-11 | ckβ11 | MIP-3β
Immunopharmacology Ligand
Comment: CCL19 is a CC family chemokine.
Species: Human
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1. Barnea G, Strapps W, Herrada G, Berman Y, Ong J, Kloss B, Axel R, Lee KJ. (2008)
The genetic design of signaling cascades to record receptor activation.
Proc Natl Acad Sci USA, 105 (1): 64-9. [PMID:18165312]
2. Leick M, Catusse J, Follo M, Nibbs RJ, Hartmann TN, Veelken H, Burger M. (2010)
CCL19 is a specific ligand of the constitutively recycling atypical human chemokine receptor CRAM-B.
Immunology, 129 (4): 536-46. [PMID:20002784]
3. Ott TR, Lio FM, Olshefski D, Liu XJ, Ling N, Struthers RS. (2006)
The N-terminal domain of CCL21 reconstitutes high affinity binding, G protein activation, and chemotactic activity, to the C-terminal domain of CCL19.
Biochem Biophys Res Commun, 348 (3): 1089-93. [PMID:16904643]
4. Sullivan SK, McGrath DA, Grigoriadis D, Bacon KB. (1999)
Pharmacological and signaling analysis of human chemokine receptor CCR-7 stably expressed in HEK-293 cells: high-affinity binding of recombinant ligands MIP-3beta and SLC stimulates multiple signaling cascades.
Biochem Biophys Res Commun, 263: 685-690. [PMID:10512740]
5. Watts AO, Verkaar F, van der Lee MM, Timmerman CA, Kuijer M, van Offenbeek J, van Lith LH, Smit MJ, Leurs R, Zaman GJ et al.. (2013)
β-Arrestin recruitment and G protein signaling by the atypical human chemokine decoy receptor CCX-CKR.
J Biol Chem, 288 (10): 7169-81. [PMID:23341447]
6. Weng Y, Siciliano SJ, Waldburger KE, Sirotina-Meisher A, Staruch MJ, Daugherty BL, Gould SL, Springer MS, DeMartino JA. (1998)
Binding and functional properties of recombinant and endogenous CXCR3 chemokine receptors.
J Biol Chem, 273 (29): 18288-91. [PMID:9660793]
7. Yoshida R, Imai T, Hieshima K, Kusuda J, Baba M, Kitaura M, Nishimura M, Kakizaki M, Nomiyama H, Yoshie O. (1997)
Molecular cloning of a novel human CC chemokine EBI1-ligand chemokine that is a specific functional ligand for EBI1, CCR7.
J Biol Chem, 272 (21): 13803-9. [PMID:9153236]
8. Yoshida R, Nagira M, Kitaura M, Imagawa N, Imai T, Yoshie O. (1998)
Secondary lymphoid-tissue chemokine is a functional ligand for the CC chemokine receptor CCR7.
J Biol Chem, 273: 7118-7122. [PMID:9507024]