Ligand id: 8314

Name: esuberaprost

Structure and Physico-chemical Properties

2D Structure
Click here for structure editor
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 8
Topological polar surface area 86.99
Molecular weight 398.21
XLogP 2.82
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Demolis JL, Robert A, Mouren M, Funck-Brentano C, Jaillon P. (1993)
Pharmacokinetics and platelet antiaggregating effects of beraprost, an oral stable prostacyclin analogue, in healthy volunteers.
J. Cardiovasc. Pharmacol., 22 (5): 711-6. [PMID:7506323]
2. Kajikawa N, Nogimori K, Murata T, Nishio S, Uchiyama S. (1989)
Specific binding of the new stable epoprostenol analogue beraprost sodium to prostacyclin receptors on human and rat platelets.
Arzneimittelforschung, 39 (4): 495-9. [PMID:2665758]