Ligand id: 8424

Name: BF-1

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 47
Molecular weight 367.16
XLogP 4.29
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Schmitz B, Ullmer C, Segelcke D, Gwarek M, Zhu XR, L├╝bbert H. (2015)
BF-1--a novel selective 5-HT2B receptor antagonist blocking neurogenic dural plasma protein extravasation in guinea pigs.
Eur. J. Pharmacol., 751: 73-80. [PMID:25666387]