compound 22e [PMID: 20167483]

Ligand id: 8504

Name: compound 22e [PMID: 20167483]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 65.98
Molecular weight 376.22
XLogP 6.51
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. He S, Dobbelaar PH, Liu J, Jian T, Sebhat IK, Lin LS, Goodman A, Guo C, Guzzo PR, Hadden M et al.. (2010)
Discovery of substituted biphenyl imidazoles as potent, bioavailable bombesin receptor subtype-3 agonists.
Bioorg. Med. Chem. Lett., 20 (6): 1913-7. [PMID:20167483]