Synonyms: cephalothin | cephalotin | Keflin®
cefalotin is an approved drug (FDA (1974))
Compound class:
Synthetic organic
Comment: Cefalotin is a semisynthetic, first generation cephalosporin belonging to the β-lactam class of antibacterial compounds [1].
![]() Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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References |
1. Boniece WS, Wick WE, Holmes DH, Redman CE. (1962)
In vitro and in vivo laboratory evaluation of cephalothin, a new broad spectrum antibiotic. J Bacteriol, 84: 1292-6. [PMID:13968796] |
2. Simon HJ, Axline SG, Vosti KL. (1965)
Cephalothin. Its in vitro antibacterial spectrum as studied in a diagnostic laboratory. Calif Med, 103 (6): 395-9. [PMID:5847736] |
3. Takeda M, Babu E, Narikawa S, Endou H. (2002)
Interaction of human organic anion transporters with various cephalosporin antibiotics. Eur J Pharmacol, 438 (3): 137-42. [PMID:11909604] |